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B12 supports the breakdown of fats, proteins, and carbs for steady energy
A 2017 meta-analysis published in Diabetes Care examined randomized controlled trials of GLP-1 receptor agonists and found no significant increase in pancreatitis risk compared to placebo or active comparators, though confidence intervals were wide due to the rarity of events
10.1016/j.taap.2022.116043 5 AgrawalS.KhazaeniB
00:24:38 Sara Klockars Thank you
Sources and references MHRA / GOV.UK: First GLP-1 tablet for weight loss approved in the UK NHS: Overweight and obesity in adults NICE NG246: Medicines for overweight and obesity New England Journal of Medicine: Oral semaglutide 25 mg in adults with overweight or obesity European Medicines Agency: Wegovy tablets for oral use positive opinion MHRA Drug Safety Update: Semaglutide and NAION MHRA Yellow Card: report a suspected side effect MHRA / GOV.UK: GLP-1 medicines for weight loss and diabetes MHRA Products: official SmPC and patient leaflets UK prescribing decisions should follow UK regulatory information, the prescriber's clinical assessment and the official UK product information when published
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